This cross-sectional study of 452 Midwestern youth (ages 9-18) found that environmental health knowledge was only weakly correlated with pro-environmental behavior (r=0.22, p<0.001), while behavior correlated more strongly with attitudes (r=0.54) and self-efficacy (r=0.51). Participation in environment-related classes, clubs, and activities was significantly associated with higher behavior (p=0.006), knowledge (p=0.003), attitude (p=0.003), and self-efficacy (p=0.02) scores in the 15-18 age group. These findings suggest that knowledge alone is insufficient to drive environmental health action, and targeted educational programming—particularly locally focused initiatives—may better equip youth to translate awareness into behavior.