A bibliometric and visualized analysis of the pathogenesis of cataracts from 1999 to 2023
Heliyon · 5 authors, 1 centre
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Annual publications rose from 76 to 277, with keyword co-occurrence analysis identifying four major research clusters: secondary cataracts, oxidative stress, gene mutations and protein abnormalities, and alteration of biological processes in lens epithelial cells.
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The study quantified publication year, authors, countries, institutions, journals, citations, and keywords, and performed co-authorship, co-citation, co-occurrence, and burst analyses. The number of annual global publications increased from 76 to 277 between 1999 and 2023. Co-occurrence analysis divided the top 100 keywords into four clusters: secondary cataracts, oxidative stress, gene mutations and protein abnormalities, and alteration of biological processes in lens epithelial cells. Research trends shifted over time from biochemical processes of proteins around 2000 to cellular and molecular pathways such as epithelial-mesenchymal transition and microRNA around 2020. Limitations include restriction to WoSCC without Scopus, PubMed, or Medline, and the sole reliance on impact factor for journal evaluation.