A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient

JPGN reports · 4 authors, 2 centres

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TL;DR

This is a case report describing a previously healthy 12-year-old boy who was found to have both Crohn disease and asymptomatic type 1 diabetes during a routine check-up.

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The paper presents a case of a 12-year-old boy evaluated for intermittent abdominal pain, diarrhea, and weight loss. Initial labs showed anemia, elevated C-reactive protein, hypoalbuminemia, and elevated fasting glucose. The patient was treated with partial enteral nutrition, prednisolone, and later infliximab. At the time of reporting, the patient remained normoglycemic with a glycated hemoglobin decrease to 5.9%. The authors discuss the rarity of this co-diagnosis and emphasize the importance of prompt detection of both conditions to prevent complications like ketoacidosis and growth failure.

STUDY TYPE

case_report

SPECIALTY

pediatrics

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100% · A

ORIGINAL PAPER

PMC10158271

A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient

JPGN reports

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ABSTRACT

Inflammatory bowel disease (IBD) is a lifelong, immune-mediated disorder that often occurs in childhood and is becoming increasingly common worldwide. Diagnosis of IBD in children remains difficult due to the spectrum of symptoms, including gastrointestinal and extraintestinal manifestations. Type 1 diabetes mellitus (T1D) is one of the most common autoimmune diseases in children and adolescents. Classic manifestations of T1D in young people include polyuria, polydipsia, abdominal pain, weight loss, and ketoacidosis. However, children with autoimmunity of pancreatic β-cells may remain euglycemic and asymptomatic for many years. An accurate and prompt diagnosis of IBD and T1D is particularly important in children because they can negatively affect growth, psychosocial function and overall well-being. We present a case in which a previously healthy child was co-diagnosed with Crohn disease and T1D during a routine pediatric evaluation in the outpatient clinic of a peripheral secondary hospital.

CITATION EXPORT

Ioanna Chranioti, George Vartzelis, Despoina Maritsi et al.. A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient. JPGN reports. (2022). https://doi.org/10.1097/PG9.0000000000000265

AUTHORS

4 · 2 CENTRES

Ioanna Chranioti, George Vartzelis, Despoina Maritsi, Maria Tsolia

From the *Pediatric Department, General Hospital of Ierapetra, Crete, Greece
†Second Pediatric Department, National and Kapodistrian University of Athens, Medical School, “P. & A. Kyriakou” Children’s Hospital, Athens, Greece.