A conceptual model of factors associated with health-related quality of life in men and women with knee osteoarthritis in Riyadh, Saudi Arabia: A multicenter cross-sectional study

Medicine · 4 authors, 2 centres

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TL;DR

This multicenter cross-sectional study of 356 adults with knee osteoarthritis found that older age, low education, severe disease, pain, and certain cultural eating habits were significantly associated with poorer physical, mental, and overall health-related quality of life for both men and women.

Full summary

583 CHARS

The study used a conceptual model to examine factors influencing health-related quality of life (HRQoL) in 356 men and women aged 45 and older with doctor-confirmed knee osteoarthritis (KOA) from five tertiary hospitals in Riyadh, Saudi Arabia. For mental health, primary education or less was associated with lower mental composite scale (MCS) scores (women: -3.07; men: -3.23), as was severe KOA (women: -4.07; men: -6.50). Limitations include a sample limited to Riyadh hospitals, potential lack of representativeness, and the cross-sectional design which cannot assess causality.

STUDY TYPE

cross-sectional

SPECIALTY

rheumatology

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ORIGINAL PAPER

PMC10378800

A conceptual model of factors associated with health-related quality of life in men and women with knee osteoarthritis in Riyadh, Saudi Arabia: A multicenter cross-sectional study

Medicine

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ABSTRACT

This study used a conceptual model to examine the factors influencing physical, mental, and overall health-related quality of life (HRQoL) in women and men aged 45 and older with knee osteoarthritis (KOA) in Saudi Arabia. In this multicenter cross-sectional study, we randomly included 356 individuals aged 45 years or above with doctor-confirmed KOA from the orthopedic and physiotherapy departments of the 5 tertiary hospitals in Riyadh, Saudi Arabia, between March 2016 and March 2017. We split all participants into men (n = 146) and women (n = 210) based on gender. A conceptual model was developed using the HRQoL influential potential factors, such as age, sex, education, occupation, and way of eating (sociodemographic), and clinical factors, such as osteoarthritis knee and its severity, duration, pain, and body mass index. The 36-item short form health survey and its subscales of the physical composite scale and mental composite scale were used to evaluate overall HRQoL, physical, and mental health, respectively. We used unadjusted multiple linear regression analyses to investigate the associations between gender-specific potential factors and HRQoL outcomes. Women and men aged between 60 and 64 years were more strongly associated significantly with less physical composite scale score by −3.17, (standard error [SE] = 1.71, P = .021) and −3.18 (SE = 1.69, P = .023) respectively, followed by the primary school or less education by −3.40 (SE = 1.27, P = . 0002), severe KOA of −8.94 (SE = 0.99, P < .001), eating on the floor bending the knee of −3.93 (SE = 1.63, P = .042), and pain of −2.39 (SE = 0.26, P < .0001). Women and men with primary school or less education significantly had low mental composite scale and 36-item short form health survey scores of −3.07 (SE = 1.22, P = .041) and −3.23 (SE = 0.99, P = .018), respectively, followed by severe KOA of −4.07 (SE = 1.22, P = .001) and −6.50 (SE = 0.83, P < .0001) and eating on the floor, extending the knee at −3.35 (SE = 1.74, P = .043). Risk factors like age, education, pain, body mass index, and severe KOA are linked to poor physical, mental, and overall HRQoL among women and men in Saudi Arabia.

CITATION EXPORT

Vishal Vennu, Amal F. Alshammary, Raed Farzan et al.. A conceptual model of factors associated with health-related quality of life in men and women with knee osteoarthritis in Riyadh, Saudi Arabia: A multicenter cross-sectional study. Medicine. (2023). https://doi.org/10.1097/MD.0000000000034175

AUTHORS

4 · 2 CENTRES

Vishal Vennu, Amal F. Alshammary, Raed Farzan, Imran Ali Khan

a Department of Rehabilitation, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
b Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.