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case_report·pediatrics, gastroenterology, immunology, surgery, endocrinology·PMC10435041

A Diagnostic Conundrum: A Case of Pediatric Autoimmune Pancreatitis

JPGN Reports · 3 authors, 2 centres

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FIDELITY 100%

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AGENT 01 · STRUCTURED SUMMARY

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TL;DR

A histological diagnosis was made, and the patient improved with corticosteroid therapy.

Full summary

291 CHARS

The patient was treated with corticosteroids and showed improvement in symptoms and labs within 6 days. A new-onset diabetes was managed with Metformin, which was later discontinued. Follow-up imaging showed resolution of the pancreatic mass, and the patient was asymptomatic one year later.

STUDY TYPE

case_report

SPECIALTY

pediatrics

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10435041

A Diagnostic Conundrum: A Case of Pediatric Autoimmune Pancreatitis

JPGN Reports

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ABSTRACT

Abstract Autoimmune pancreatitis (AIP) is rare cause of abdominal pain in children who often present with obstructive jaundice, mimicking malignancy. An investigation of clinical symptoms, serology, imaging, and histopathology is necessary for diagnosis. We report a 10-year-old female presenting with abdominal pain and jaundice, ultimately found to have AIP after confirmation with tissue pathology. Our patient’s prompt response to corticosteroid initiation is characteristic of this disease state. AIP has 2 subtypes, the second of which is more frequently found in children. Our patient’s pathology did not fit perfectly with either subtype, but had features found in each one. While diagnostic criteria for AIP have not established in pediatrics, our case highlights the combination of clinical symptoms, imaging, and histopathology that children classically present with. While rare, the diagnosis of AIP is associated with comorbidities and must be considered in any child presenting with a pancreatic mass or biliary stricture. Keywords: autoimmune pancreatitis (AIP), obstructive jaundice, abdominal pain, ERCP, endoscopic ultrasound, fine needle biopsy, malignancy

CITATION EXPORT

Naseem Ravanbakhsh, Nick Shillingford, Travis L Piester. A Diagnostic Conundrum: A Case of Pediatric Autoimmune Pancreatitis. JPGN Reports. (2023). https://doi.org/10.1097/PG9.0000000000000326

AUTHORS

3 · 2 CENTRES

Naseem Ravanbakhsh, Nick Shillingford, Travis L Piester

From the *Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital Los Angeles, Los Angeles, CA, USA
†Division of Pathology, Children’s Hospital Los Angeles, Los Angeles, CA, USA.