A life for autoimmune blistering diseases: in memoriam Detlef Zillikens

Frontiers in Immunology · 21 authors, 13 centres

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TL;DR

It describes his career trajectory, the establishment of a major research center in Lübeck, and his key collaborations, notably with Euroimmun, which led to the development of widely used serological assays and Biochip technology for diagnosing AIBDs like bullous pemphigoid and pemphigus.

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narrative_review

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dermatology

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ORIGINAL PAPER

PMC10621786

A life for autoimmune blistering diseases: in memoriam Detlef Zillikens

Frontiers in Immunology

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ABSTRACT

Abstract Detlef Zillikens, MD, director and chair of the Department of Dermatology at the University of Lübeck, Lübeck, Germany, died in September 2022, aged only 64. He dedicated his professional life to autoimmune blistering diseases (AIBDs) and built his department into one of the world’s leading centers for these diseases. Herein, his professional life and the impact on the field of AIBDs and the research landscape at the University of Lübeck are addressed. With his warm, integrative, open-minded, ever-optimistic attitude, he was a highly reliable colleague, mentor, and friend to many in the field including each of the authors. Combined with his in-depth knowledge of dermatology, interest in many fields of life science, and hard work, Detlef Zillikens initiated the founding of two independent research institutes, the Lübeck Institute of Experimental Dermatology and the Institute and Comprehensive Center for Inflammation Medicine. He was also instrumental in establishing the Center for Research on Inflammation of the Skin, where in a new research building, over 140 scientists pursue research questions related to skin inflammation. By inviting numerous researchers and clinicians to his department and hosting two large international meetings, he brought the field of AIBDs much closer together and inspired multiple national and international research initiatives. His ideas will live on and grow in many of his colleagues and mentees. Keywords: autoimmune blistering diseases, pemphigoid, pemphigus, autoantibody, immuno-fluorescence, dermatology, clinician scientists

CITATION EXPORT

Jennifer E Hundt, Christian D Sadik, Nina van Beek et al.. A life for autoimmune blistering diseases: in memoriam Detlef Zillikens. Frontiers in Immunology. (2023). https://doi.org/10.3389/fimmu.2023.1291590

AUTHORS

21 · 13 CENTRES

Jennifer E Hundt, Christian D Sadik, Nina van Beek, Hauke Busch, Frédéric Caux, Matthias Goebeler, Christoph M Hammers, Karin Hartmann, Takashi Hashimoto, Saleh Ibrahim, Michael Kasperkiewicz, Dedee F Murrell, Andreas Recke, Christian Rose, Nina Schumacher, Iakov Shimanovich, Cassian Sitaru, Patrick Terheyden, Diamant Thaçi, Ralf J Ludwig, Enno Schmidt

1 Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany
2 Department of Dermatology, University of Lübeck, Lübeck, Germany
3 Department of Dermatology, Groupe Hospitalier Paris Seine-Saint-Denis, AP-HP, Bobigny, France
4 Department of Dermatology, University of Würzburg, Würzburg, Germany
5 Department of Dermatology, University of Kiel, Kiel, Germany
6 Department of Dermatology, Basel, Switzerland
7 Department of Dermatology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan
8 Khalifa University, Abu Dhabi, United Arab Emirates
9 Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States
10 Department of Dermatology, St George Hospital, University of New South Wales (UNSW), Sydney, NSW, Australia
11 Dermatohistologisches Einsendelabor Lübeck, Lübeck, Germany
12 Department of Dermatology, Faculty of Medicine, Medical Center-University of Freiburg, Freiburg, Germany
13 Institute and Comprehensive Center for Inflammation Medicine (CCIM), University of Lübeck, Lübeck, Germany