Although all included studies reported significant associations, no single microbiota feature correlated with growth consistently across studies, reflecting wide heterogeneity in study populations, growth definitions, and analytical methods.
Gut Microbes · 3 authors, 2 centres
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Although all included studies reported significant associations, no single microbiota feature correlated with growth consistently across studies, reflecting wide heterogeneity in study populations, growth definitions, and analytical methods.
This PRISMA-guided systematic review identified 14 human studies reporting associations between neonatal gut microbiota signatures and postnatal growth failure in preterm infants. The authors conducted a qualitative synthesis and an exploratory secondary data analysis to illustrate how growth definition choices affect results. No microbiota feature was consistently associated with growth across all or most studies.