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TL;DR
This narrative review synthesizes evidence on the relationship between obesity and type 2 diabetes.
Wiener Klinische Wochenschrift · 10 authors, 9 centres
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This narrative review synthesizes evidence on the relationship between obesity and type 2 diabetes.
This narrative review synthesizes evidence on the relationship between obesity and type 2 diabetes. The review discusses modern pharmacotherapies, including GLP-1 analogs and the dual GIP/GLP-1 agonist tirzepatide, as important for treating both conditions. Regarding bariatric surgery, it is indicated for patients with diabetes and BMI >35 kg/m^2. The review notes that surgery is superior to medication alone in comparative studies, citing the 5-year STAMPEDE trial, but cautions that surgery does not guarantee a permanent cure and lifelong follow-up is needed.