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TL;DR
This study cultured Helicobacter pylori from 50 treatment-naïve children in northeast Poland and tested antibiotic susceptibility. It found a high rate of resistance, with only 48% of strains susceptible to all three tested antibiotics.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research · 6 authors, 2 centres
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This study cultured Helicobacter pylori from 50 treatment-naïve children in northeast Poland and tested antibiotic susceptibility. It found a high rate of resistance, with only 48% of strains susceptible to all three tested antibiotics.
This prospective cohort study assessed antibiotic resistance in Helicobacter pylori from 50 treatment-naïve children in northeast Poland diagnosed via gastric or duodenal biopsy between February 2019 and May 2022. Strains were cultured and tested for resistance to clarithromycin, metronidazole, and amoxicillin using the E-test method. The central result was that resistance was most common to clarithromycin (38%), followed by metronidazole (30%) and amoxicillin (26%). Notably, only 48% of the strains were susceptible to all three antibiotics. The study is limited by its small sample size and the inability to compare results with an adult population from the same region. The findings provide regional data on antibiotic resistance in pediatric H. pylori infections, which may inform local treatment strategies.