Anxiety, depression, and concentration in cancer survivors: National Health and Nutrition Examination Survey results

Supportive Care in Cancer · 4 authors, 6 centres

AI SUMMARY

FIDELITY 100%

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

“

TL;DR

Survey-weighted logistic regression adjusted for age, gender, race/ethnicity, and education found no significant difference in anxiety (45.8% vs.

Full summary

700 CHARS

Survey-weighted logistic regression adjusted for age, gender, race/ethnicity, and education found no significant difference in anxiety (45.8% vs. Concentration difficulties were more prevalent among cancer survivors (11.3% vs. A secondary analysis found that prevalence of mental health symptoms was not related to time since diagnosis among survivors. Anxiety and depression were highly correlated (r = 0.81) and moderately correlated with concentration difficulties. Tumor-specific analyses suggested higher odds of anxiety and depression for upper gastrointestinal cancers. Results suggest concentration difficulties may be a distinct concern for cancer survivors warranting further investigation.

STUDY TYPE

cross-sectional

SPECIALTY

oncology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10105664

Anxiety, depression, and concentration in cancer survivors: National Health and Nutrition Examination Survey results

Supportive Care in Cancer

READ THE FULL PAPER

ABSTRACT

Abstract Purpose We report on prevalence of anxiety, depression, and concentration difficulties and their associations in survivors of cancer in a nationally representative sample up to 25 years after diagnosis. Methods Using the National Health and Nutrition Examination Survey (NHANES) data from 2015 to 2018, participants between the ages of 18 and 79 self-reported on cancer history, symptoms of anxiety, depression, and difficulties with concentration. Results Of 10,337 participants, 691 (6.7%) reported a previous diagnosis of cancer; the median time since diagnosis was 8 years. Prevalence was similar between those with and without cancer for anxiety (45.8% versus 46.9%) and depression (19.7% versus 20.0%). Concentration difficulties were more common (11.3% versus 9.0%) for those with a history of cancer compared to those without (adjusted OR = 1.38, 95% CI: 1.00–1.90). Prevalence of mental health symptoms was not related to time since diagnosis. Anxiety and depression were highly correlated ( r = 0.81, 95% CI: 0.74–0.86) and moderately correlated with difficulty with concentration ( r = 0.52, 95%CI: 0.40–0.64 and r = 0.64, 95% CI: 0.53–0.74 respectively). Conclusions Difficulty with concentration was more commonly reported by participants with than without a cancer history. Report of anxiety and depression was no different between participants with and without a history of cancer. Anxiety, depression, and difficulties with concentration were strongly related. Further research is needed to explore if there is a causal association, and if so, the direction of these correlations, so that interventions may be appropriately targeted. Supplementary Information The online version contains supplementary material available at 10.1007/s00520-023-07710-w. Keywords: Anxiety, Cancer, Cancer survivors, Concentration, Depression, Oncology

CITATION EXPORT

Joanna E Fardell, Chase M Irwin, Janette L Vardy et al.. Anxiety, depression, and concentration in cancer survivors: National Health and Nutrition Examination Survey results. Supportive Care in Cancer. (2023). https://doi.org/10.1007/s00520-023-07710-w

AUTHORS

4 · 6 CENTRES

Joanna E Fardell, Chase M Irwin, Janette L Vardy, Melanie L Bell

1Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia
2UNSW Medicine & Health, School of Clinical Medicine, UNSW Sydney, Kensington, Australia
3Western Sydney Youth Cancer Service, Westmead Hospital, Sydney, Australia
4Kids Cancer Centre, Sydney Children’s Hospital, Level 1 South, Randwick, Sydney, Australia
5Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724 USA
6Concord Cancer Centre, Concord Repatriation General Hospital, Sydney, New South Wales Australia