The review confirms that overweight and obesity may negatively influence ovarian function in women of reproductive age.
Nutrients · 8 authors, 4 centres
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The review confirms that overweight and obesity may negatively influence ovarian function in women of reproductive age.
This systematic review followed the PRISMA framework and assessed study quality using the Cochrane Collaboration Risk of Bias tool. In 12 of the included articles (54.5%), a relationship between nutritional status and ovarian reserve was demonstrated. Eleven studies showed lower AMH levels in obese women, and lower AFC and oocyte quality were observed in overweight and obese women. The authors noted that obesity may induce ovarian oxidative stress through chronic inflammation and lipotoxicity. Limitations include restriction to English and Spanish publications, searching only three databases, and exclusion of women undergoing assisted reproductive techniques. The authors suggest further studies are needed to identify specific dietary factors affecting ovarian reserve.