cross-sectional·epidemiology, public health, nutrition, oncology, endocrinology·PMC10212079
Association of dietary sodium intake with impaired fasting glucose in adult cancer survivors: A population-based cross-sectional study
PLOS ONE · 4 authors, 5 centres
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In a population-based cross-sectional study of 1,052 adult cancer survivors from the KNHANES (2013–2018), higher dietary sodium intake was marginally associated with increased odds of impaired fasting glucose (IFG), with a significant linear trend across sodium intake categories defined by the AHA recommendation.
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This cross-sectional study used data from the sixth and seventh Korea National Health and Nutrition Examination Survey (KNHANES, 2013–2018) to examine the association between dietary sodium intake categorized per the AHA recommendation and IFG in 1,052 community-dwelling adult cancer survivors without diabetes. A multiple logistic regression model adjusted for demographic, lifestyle, and health status variables was used to compute odds ratios and 95% confidence intervals. The adjusted OR for IFG was 2.67 (95% CI: 0.59–12.18) among survivors consuming ≥4,000 mg/day compared to <1,500 mg/day, with a significant linear trend (P=0.036) across categories, though individual category comparisons were statistically nonsignificant. The authors characterized this as a marginal association. Limitations include the cross-sectional design precluding causal inference, reliance on self-reported dietary data at a single time point, a relatively small sample from a single country, and inability to fully account for all potential confounders.