JAMA Network Open · 7 authors, 5 centres
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The primary results show that lower socioeconomic status (SES) was independently associated with lower restricted directional diffusion (RSI-RND), greater restricted isotropic diffusion (RSI-RNI), and lower fractional anisotropy (DTI-FA) in various white matter tracts.
The primary results show that lower socioeconomic status (SES) was independently associated with lower restricted directional diffusion (RSI-RND), greater restricted isotropic diffusion (RSI-RNI), and lower fractional anisotropy (DTI-FA) in various white matter tracts. Mediation analyses indicated that greater body mass index (BMI) and poorer cognitive performance partially explained these associations. The study's large, diverse sample is a strength, but the cross-sectional design prevents causal inference. The findings suggest that obesity and cognitive enrichment are plausible pathways linking socioeconomic disadvantage to differences in children's white matter microstructure.
