Annals of Indian Academy of Neurology
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This paper presents multiple studies on neurological conditions, with the most detailed component being a cross-sectional comparison of non-motor symptoms (NMS) in Parkinson's disease (PD), multiple system atrophy (MSA), and progressive supranuclear palsy (PSP) in 204 patients. NMS were significantly more prevalent and disabling in atypical parkinsonian syndromes than in PD.
This source comprises multiple studies, the most complete being a cross-sectional analysis of non-motor symptoms (NMS) in Parkinsonian syndromes. Patients were assessed using the Non-Motor Symptom Scale (NMSS), MDS-UPDRS Part III, PDQ-39, Modified Hoehn & Yahr, and MMSE. The study found that 98% of patients had at least one NMS, with significantly greater NMS burden in MSA and PSP compared to PD. In PD, sleep dysfunction was the most severely affected domain. A significant positive correlation was observed between NMSS scores and both UPDRS motor scores and PDQ-39 scores across all groups.
