Pharmaceutics · 4 authors, 3 centres
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This is a narrative review of polymer-based biomaterials and 3D bioprinting techniques for dental tissue engineering. The central result is a comprehensive overview of natural, synthetic, and composite polymers, along with their applications in preclinical studies for regenerating dental tissues like dentin, pulp, and alveolar bone.
This narrative review surveys the current landscape of polymeric biomaterials and 3D bioprinting for dental tissue regeneration. It categorizes polymers into natural (e.g., collagen, gelatin, alginate), synthetic (e.g., PLGA, PLA, PCL), and composite materials, detailing their properties and fabrication methods. The review summarizes findings from preclinical studies, such as the use of erythropoietin-loaded collagen scaffolds to enhance blood vessel formation and the implantation of 3D-printed PCL/β-TCP scaffolds in animal models to improve alveolar bone formation. The review concludes by identifying future directions, including the integration of bioprinting with advanced imaging for clinical translation.
