Breaking Up Evening Sitting with Resistance Activity Improves Postprandial Glycemic Response: A Randomized Crossover Study

Medicine and Science in Sports and Exercise · 6 authors, 3 centres

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TL;DR

No significant difference was observed for triglyceride response, and effects appeared consistent across BMI categories.

Full summary

1,022 CHARS

This randomized crossover study evaluated whether interrupting prolonged evening sitting with resistance exercise breaks could improve postprandial metabolic responses. Thirty healthy adults across three BMI categories completed two arms: uninterrupted sitting for 4 hours and sitting interrupted every 30 minutes by 3-minute resistance exercise bouts, with two meals provided during each session beginning at approximately 1700 h. Compared with prolonged sitting, activity breaks reduced glucose and insulin incremental area under the curve by 31.5% and 26.6%, respectively, with no significant difference observed for triglycerides. The exploratory BMI subgroup interaction was not statistically significant, and the study noted it would require approximately 120 participants to be adequately powered for interaction effects. This was the first evening-sitting study to include healthy-weight participants. Findings suggest evening activity breaks may improve cardiometabolic health indicators regardless of bodyweight.

STUDY TYPE

RCT

SPECIALTY

endocrinology

SUMMARISED BY

AI pipeline

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100% · A

ORIGINAL PAPER

PMC10348652

Breaking Up Evening Sitting with Resistance Activity Improves Postprandial Glycemic Response: A Randomized Crossover Study

Medicine and Science in Sports and Exercise

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ABSTRACT

ABSTRACT Introduction Interrupting sedentary time during the day reduces postprandial glycemia (a risk factor for cardiometabolic disease). However, it is not known if benefits exist for postprandial glucose, insulin and triglyceride responses in the evening, and if these benefits differ by body mass index (BMI) category. Methods In a randomized crossover study, 30 participants (25.4 ± 5.4 yr old; BMI 18.5–24.9: n = 10, BMI 25–29.9: n = 10, BMI ≥30: n = 10) completed two intervention arms, beginning at ~1700 h: prolonged sitting for 4 h, and sitting with regular activity breaks of 3 min of resistance exercises every 30 min. Plasma glucose, insulin, and triglyceride concentrations were measured in response to two meals fed at baseline and 120 min. Four-hour incremental area under the curve was compared between interventions. Moderation by BMI status was explored. Results Overall, when compared with prolonged sitting, regular activity breaks lowered plasma glucose and insulin incremental area under the curve by 31.5% (95% confidence interval = −49.3% to −13.8%) and 26.6% (−39.6% to −9.9%), respectively. No significant differences were found for plasma triglyceride area under the curve. Interactions between BMI status and intervention was not statistically significant. Conclusions Interventions that interrupt sedentary time in the evening may improve cardiometabolic health by some magnitude in all participants regardless of bodyweight.

CITATION EXPORT

JENNIFER T. GALE, DOROTHY L. WEI, JILLIAN J. HASZARD et al.. Breaking Up Evening Sitting with Resistance Activity Improves Postprandial Glycemic Response: A Randomized Crossover Study. Medicine and Science in Sports and Exercise. (2023). https://doi.org/10.1249/MSS.0000000000003166

AUTHORS

6 · 3 CENTRES

JENNIFER T. GALE, DOROTHY L. WEI, JILLIAN J. HASZARD, RACHEL C. BROWN, RACHAEL W. TAYLOR, MEREDITH C. PEDDIE

1Department of Human Nutrition, University of Otago, Dunedin, NEW ZEALAND
2Biostatistics Centre, University of Otago, Dunedin, NEW ZEALAND
3Department of Medicine, University of Otago, Dunedin, NEW ZEALAND