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Laboratory evaluation revealed declining hemoglobin from 12 g/dl to 8.4 g/dl, platelet count of 144×1000/µl, undetectable haptoglobin, lactate dehydrogenase of 705 U/L, and reticulocyte count of 3.11%, consistent with microangiopathic hemolytic anemia.
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Laboratory evaluation revealed declining hemoglobin from 12 g/dl to 8.4 g/dl, platelet count of 144×1000/µl, undetectable haptoglobin, lactate dehydrogenase of 705 U/L, and reticulocyte count of 3.11%, consistent with microangiopathic hemolytic anemia. Serum creatinine had risen from 0.8 mg/dl to 2.2 mg/dl with proteinuria of 8.6 g/g creatinine. Gemcitabine was discontinued, and kidney function improved, with creatinine decreasing to 1.0 mg/dl and proteinuria to 0.22 g/g creatinine at 6 months.