SEARCHCOHORTpediatrics, infectious disease

cohort·pediatrics, infectious disease, epidemiology, public health, gastroenterology·PMC10145719

Clinical characteristics and influencing factors of infectious diarrhea in preschool children: An observational study

Medicine · 4 authors, 2 centres

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TL;DR

It found rotavirus vaccination, hand-washing, and other hygiene practices were protective, while exposure to diarrhea and indoor pests were risk factors.

Full summary

586 CHARS

Pathogen analysis identified salmonella (15.77%), rotavirus (13.85%), and shigella (11.54%) as the most common. Onset peaked in winter and summer months. Multivariate logistic regression analysis identified seven factors: rotavirus vaccination, regular hand-washing, tableware disinfection, separate preparation of cooked and raw foods, and regular lactobacillus product intake were protective. Recent exposure to diarrhea and indoor flies/cockroaches were risk factors. Limitations include a single-site urban sample and some unclear pathogen origins, which may limit generalizability.

STUDY TYPE

cohort

SPECIALTY

pediatrics

SUMMARISED BY

AI pipeline

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100% · A

ORIGINAL PAPER

PMC10145719

Clinical characteristics and influencing factors of infectious diarrhea in preschool children: An observational study

Medicine

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ABSTRACT

Abstract Infectious diarrhea is a common disease in preschool children, but the pathogenic species, origins, and influencing factors remain debatable. Therefore, more studies are required to solve these debatable topics. A number of 260 eligible preschool children diagnosed with infectious diarrhea in our hospital were enrolled in the infection group. Meanwhile, a number of 260 matched healthy children from the health center were enrolled in the control group. The pathogenic species and origins, the time of onset of infectious diarrhea in the infection group, demographic data, exposure history, hygiene habits, dietary habits, and other variables in both groups were initially collected from medical documents. In addition, a questionnaire was used to complete and confirm study variables through face-to-face or telephone interviews. Then, the univariate and multivariate regression analyses were used to screen the influencing factors of infectious diarrhea. Among 260 infected children, salmonella (15.77%), rotavirus (13.85%), shigella (11.54%), vibrio (10.38%), and norovirus (8.85%) were the top 5 common pathogens; January (13.85%), December (12.69%), August (12.31%), February (11.92%), and July (8.46%) were the top 5 frequent times of infectious diarrhea. The distribution of onset time for infectious diarrhea was commonly found in winter and summer, and the pathogens always originated from foods. The results of multivariate regression analysis showed that recent exposure to diarrhea, flies, and/or cockroaches indoors were the 2 risk factors for infectious diarrhea; Meanwhile, rotavirus vaccination, regular hand-washing, tableware disinfection, separate preparation of cooked and raw foods, and regular intake of lactobacillus products were the 5 protective factors for infectious diarrhea in preschool children. Infectious diarrhea has a diversity of pathogenic species, origins, and influencing factors in preschool children. Activities focusing on these influencing factors such as rotavirus vaccination, consumption of lactobacillus products, and other conventional factors would be beneficial to preschool children’s health. Keywords: infectious diarrhea, influencing factor, pathogens, preschool children

CITATION EXPORT

Mu-Heng Chen, Su-Han Deng, Ming-Huan Wang et al.. Clinical characteristics and influencing factors of infectious diarrhea in preschool children: An observational study. Medicine. (2023). https://doi.org/10.1097/MD.0000000000033645

AUTHORS

4 · 2 CENTRES

Mu-Heng Chen, Su-Han Deng, Ming-Huan Wang, Xu-Ke Yan

a Department of Pediatrics, The Fenghua People’s Hospital, Ningbo City, Zhejiang Province, China
b Department of Pediatrics, The Ningbo Women and Children’s Hospital, Ningbo City, Zhejiang Province, China.