BMC Geriatrics · 16 authors, 10 centres
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This cohort profile describes the GRACE study, which recruited 279 permanent residents from five South Australian residential aged care facilities to examine risk factors for antimicrobial resistance carriage and transmission. Comparisons with a national registry showed the cohort was broadly representative of the Australian aged care population in age, sex, duration of care, and health conditions.
The GRACE study recruited 279 participants from five South Australian residential aged care facilities between March 2019 and March 2020, achieving a 75% recruitment rate. The cohort had a median age of 88.6 years, was predominantly female (71.7%), and had a median residential stay of 681 days. Over half had a dementia diagnosis (54.5%), and 61% had received antibiotics in the preceding 12 months. Comparison with the ROSA national registry showed similar age, sex, duration of residential care, health conditions, and dementia diagnoses, though GRACE participants had higher care needs and antibiotic exposure. Limitations include exclusive metropolitan and not-for-profit facility participation, exclusion of respite and palliative care residents, impact of the COVID-19 pandemic on final sample size, and lack of ethnicity data.
