SEARCHNARRATIVE_REVIEWgastroenterology, oncology

narrative_review·gastroenterology, oncology, epidemiology, public health, internal medicine·PMC10182334

Colon Cancer Screening Methods: 2023 Update

Cureus · 7 authors, 6 centres

AI SUMMARY

FIDELITY 100%

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

“

TL;DR

This narrative review summarizes colorectal cancer screening modalities including stool-based tests, radiologic imaging, endoscopic examinations, and biomarkers, outlining the sensitivity, specificity, benefits, and challenges of each approach.

Full summary

451 CHARS

This narrative review synthesizes current evidence on CRC screening modalities, covering stool-based tests (FOBT, FIT, FIT-DNA), radiologic tests (CTC, double contrast barium enema), endoscopic examinations (flexible sigmoidoscopy, colonoscopy, colon capsule endoscopy), and circulating biomarkers. Limitations include reliance on open-access journals published between 2007 and 2023, potential exclusion of subscription-based and non-English studies.

STUDY TYPE

narrative_review

SPECIALTY

gastroenterology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10182334

Colon Cancer Screening Methods: 2023 Update

Cureus

READ THE FULL PAPER

ABSTRACT

Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. National screening guidelines have been implemented to identify and remove precancerous polyps before they become cancer. Routine CRC screening is advised for people with average risk starting at age 45 because it is a common and preventable malignancy. Various screening modalities are currently in use, ranging from stool-based tests (fecal occult blood test (FOBT), fecal immunochemical test (FIT), and FIT-DNA test), radiologic tests (computed tomographic colonography (CTC), double contrast barium enema), and visual endoscopic examinations (flexible sigmoidoscopy (FS), colonoscopy, and colon capsule endoscopy (CCE)) with their varying sensitivity and specificity. Biomarkers also play a vital role in assessing the recurrence of CRC. This review offers a summary of the current screening options, including biomarkers available to detect CRC, highlighting the benefits and challenges encompassing each screening modality.

CITATION EXPORT

Maleesha Jayasinghe, Omesh Prathiraja, Dilushini Caldera et al.. Colon Cancer Screening Methods: 2023 Update. Cureus. (2023). https://doi.org/10.7759/cureus.37509

AUTHORS

7 · 6 CENTRES

Maleesha Jayasinghe, Omesh Prathiraja, Dilushini Caldera, Rahul Jena, James Anwar Coffie-Pierre, Minollie Suzanne Silva, Ozair S Siddiqui

1 Medicine, Nanjing Medical University, Nanjing, CHN
2 Medicine and Surgery, Nanjing Medical University, Nanjing, CHN
3 Medicine, 37 Military Hospital, Accra, GHA
4 Neurology/Internal Medicine, Bharati Vidyapeeth Medical College/Bharati Hospital, Pune, IND
5 Internal Medicine, Nanjing Medical University, Nanjing, CHN
6 Medicine, GMERS Medical College and Hospital, Dharpur-Patan, Patan, IND

EDITOR / REVIEWER

Alexander Muacevic, John R Adler