This retrospective cohort reviewed 44 bariatric surgery patients with weight regain who received anti-obesity medications plus intensive lifestyle modification at an academic obesity center, finding mean weight loss of 10.7 kg at 12 months.
Obesity Science & Practice · 7 authors, 5 centres
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This retrospective cohort reviewed 44 bariatric surgery patients with weight regain who received anti-obesity medications plus intensive lifestyle modification at an academic obesity center, finding mean weight loss of 10.7 kg at 12 months.
Mean weight loss after medical intervention at 3-, 6-, and 12-month time points was 4.4 kg, 7.3 kg, and 10.7 kg, respectively. At 12 months, individuals prescribed three or more AOMs lost more weight than those prescribed one (14.5 kg vs. 4.9 kg, p<0.05), irrespective of age, gender, comorbidities, initial weight or BMI, surgery type, or GLP-1 use. RYGB patients lost less weight overall than VSG patients (7.4% vs. 14.8% TWL, p<0.05). Limitations include small sample size, retrospective design, and reduced cohort at 12 months (n=25).