PLOS ONE · 7 authors, 6 centres
This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.
This is a protocol for a planned systematic review and meta-analysis that will assess the rates and determinants of complications following laparoscopy and laparotomy surgeries for endometriosis. No results are reported; it outlines the methodology for a future review.
The review aims to synthesize evidence from retrospective and prospective cohorts or trials (with at least 30 participants) published after 2011, excluding cancer or other benign gynecologic surgeries. The primary outcome is a composite of intraoperative and postoperative complications within 30 days and three months. Secondary outcomes include specific complications and their determinants. Planned analyses include subgroup analyses by surgical approach, procedure, endometriosis type, and indication, with sensitivity analyses for low-risk-of-bias studies. The protocol acknowledges anticipated limitations such as high patient heterogeneity and potential confounding bias. The intended output is a synthesis of complication rates to inform patient decisions and identify areas for care improvement.
