“
TL;DR
This multimodal observational study used NHANES data from 2007 to 2020 to examine the association between hysterectomy and depressive symptoms in a multi-ethnic U.S. population sample.
Scientific Reports · 7 authors, 3 centres
This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.
This multimodal observational study used NHANES data from 2007 to 2020 to examine the association between hysterectomy and depressive symptoms in a multi-ethnic U.S. population sample.
This multimodal observational study used NHANES data from 2007 to 2020 to examine the association between hysterectomy and depressive symptoms in a multi-ethnic U.S. population sample. Depression was assessed using the PHQ-9, with a score of 5 or above indicating depression positivity. The study compared four surgical procedure categories: hysterectomy alone, oophorectomy alone, hysterectomy with oophorectomy, and no surgery, using regression analysis after propensity score matching for demographic factors and medical histories. The authors report that hysterectomy was a risk factor for postoperative depression and that oophorectomy alone was not associated with positive depression. Notably, simultaneous removal of both the uterus and ovaries further increased depression risk. Women after hysterectomy had more depressive symptoms including little interest, feeling down, and trouble concentrating. Limitations include the cross-sectional design, which precludes determining temporal relationships, and potential residual confounding from unmeasured factors such as personality, preoperative psychosocial status, perioperative pain, and postoperative infection.