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TL;DR
It found a significant increase in the risk of menstrual disturbances, particularly latency and heavy bleeding, after vaccination.
New Microbes and New Infections · 3 authors, 2 centres
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It found a significant increase in the risk of menstrual disturbances, particularly latency and heavy bleeding, after vaccination.
This cross-sectional study analyzed self-reported data from an online survey of 455 Iranian women aged 15-55. Using a self-controlled case-series design, researchers estimated the relative risk of various menstrual disturbances following the first, second, and third doses of COVID-19 vaccines. The study found that over 50% of women reported no disturbance, but 18.4% reported disturbances after the first dose, 20.9% after the second, and 12.5% after the third. Latency of menstruation (19.4%) and premature menstruation (17.1%) were the most common reported issues. The authors conclude there is a significant increase in menstrual disturbances post-vaccination, suggesting immune activation may be a mechanism.