BMJ Global Health · 10 authors, 2 centres
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A qualitative study with 108 stakeholders in Mali identified four delivery strategies for the RTS,S/AS01E malaria vaccine, with the preferred strategy being age-based priming doses plus seasonal booster doses all delivered via the routine EPI programme. Participants stressed that supportive interventions such as communications, reminders, and community tracing would be needed for this strategy to achieve adequate coverage.
This qualitative study used in-depth interviews with 108 national, regional, and district-level programme managers, health workers, caregivers, and community stakeholders, plus a national-level workshop, to identify delivery strategies for RTS,S/AS01E alongside seasonal malaria chemoprevention in Mali. Four strategies were identified: age-based vaccination via EPI, seasonal vaccination via mass vaccination campaigns, a combination of age-based priming via EPI and seasonal boosters via campaigns, and a combination of age-based priming and seasonal boosters all via routine EPI. The fourth strategy was preferred at the national workshop because it provides early childhood protection and ongoing seasonal protection while avoiding the health system burden of mass campaigns. Supportive interventions including communications, reminders, defaulter tracing, and training of health workers were recommended as necessary for the preferred strategy to succeed.
