SEARCHCOHORTpulmonology, pediatrics

cohort·pulmonology, pediatrics, nutrition, epidemiology, public health·PMC10022039

Dietary patterns, lung function and asthma in childhood: a longitudinal study

Respiratory Research · 7 authors, 7 centres

AI SUMMARY

FIDELITY 100%

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

“

TL;DR

No associations were found with incident asthma.

Full summary

520 CHARS

This analysis used data from the Avon Longitudinal Study of Parents and Children to investigate associations between dietary patterns in mid-childhood and later respiratory outcomes. Post-bronchodilator lung function was measured by spirometry at 15.5 years, and incident asthma was defined by new doctor diagnoses at age 11 or 14. In multivariable-adjusted models, a higher 'health-conscious' pattern score was associated with higher FEV1 and FVC, while a higher 'processed' pattern score was associated with lower FVC.

STUDY TYPE

cohort

SPECIALTY

pulmonology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10022039

Dietary patterns, lung function and asthma in childhood: a longitudinal study

Respiratory Research

READ THE FULL PAPER

ABSTRACT

Abstract Background Longitudinal epidemiological data are scarce examining the relationship between dietary patterns and respiratory outcomes in childhood. We investigated whether three distinct dietary patterns in mid-childhood were associated with lung function and incident asthma in adolescence. Methods In the Avon Longitudinal Study of Parents and Children, ‘processed’, ‘traditional’, and ‘health-conscious’ dietary patterns were identified using principal components analysis from food frequency questionnaires at 7 years of age. Post-bronchodilator forced expiratory volume in 1 s (FEV 1 ), forced vital capacity (FVC), and forced expiratory flow at 25–75% of FVC (FEF 25–75 ) were measured at 15.5 years and were transformed to z-scores based on the Global Lung Function Initiative curves. Incident asthma was defined by new cases of doctor-diagnosed asthma at age 11 or 14 years. Results In multivariable-adjusted models, the ‘health-conscious’ pattern was positively associated with FEV 1 (regression coefficient comparing top versus bottom quartile of pattern score 0.16, 95% CI 0.01 to 0.31, P for trend 0.04) and FVC (0.18, 95% CI 0.04 to 0.33, P for trend 0.02), while the ‘processed’ pattern was negatively associated with FVC (− 0.17, 95% CI − 0.33 to − 0.01, P for trend 0.03). Associations between the ‘health-conscious’ and ‘processed’ patterns and lung function were modified by SCGB1A1 and GPX4 gene polymorphisms. We found no evidence of an association between the ‘traditional’ pattern and lung function, nor between any pattern and FEF 25–75 or incident asthma. Conclusions A ‘health-conscious’ diet in mid-childhood was associated with higher subsequent lung function, while a diet high in processed food was associated with lower lung function. Supplementary Information The online version contains supplementary material available at 10.1186/s12931-023-02383-9. Keywords: Dietary pattern, Lung function, Asthma, Childhood, Diet, ALSPAC

CITATION EXPORT

Mohammad Talaei, Pauline M Emmett, Raquel Granell et al.. Dietary patterns, lung function and asthma in childhood: a longitudinal study. Respiratory Research. (2023). https://doi.org/10.1186/s12931-023-02383-9

AUTHORS

7 · 7 CENTRES

Mohammad Talaei, Pauline M Emmett, Raquel Granell, Hossein Tabatabaeian, Kate Northstone, Anna Bergström, Seif O Shaheen

1Wolfson Institute of Population Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ UK
2Centre for Academic Child Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
3MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
4Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
5Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
6Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
7Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden