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other·oncology, gastroenterology, geriatrics, internal medicine, surgery·PMC10144337

Diode Laser Therapy for Radiation-Induced Vascular Ectasia: Long-Term Results and Cost Analysis

Life · 4 authors, 2 centres

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TL;DR

This retrospective study evaluated endoscopic diode laser therapy for chronic radiation proctitis in 24 patients, finding it safe, effective for controlling bleeding, and cost-efficient as an outpatient procedure without requiring sedation or anticoagulant suspension.

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This retrospective study analyzed 24 patients with chronic radiation proctitis treated with endoscopic diode laser therapy between 2010 and 2021. Patients received a median of two laser sessions in an outpatient setting without sedation. The study reported no complications during or after procedures, and bleeding completely resolved in 21 patients (88%) with improvement in two others, for a 96% global improvement rate. Notably, antiplatelet or anticoagulant therapy was not suspended during treatment. The mean cost per session was EUR 473.4. The study concludes the therapy is safe, effective, and cost-efficient. The findings support diode laser therapy as a viable option for this frail patient population.

STUDY TYPE

other

SPECIALTY

oncology

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AI pipeline

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100% · A

ORIGINAL PAPER

PMC10144337

Diode Laser Therapy for Radiation-Induced Vascular Ectasia: Long-Term Results and Cost Analysis

Life

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ABSTRACT

Background: Collateral damage to surrounding healthy tissues has been reported in patients who undergo radiation therapy for pelvic malignancies. This study aimed to evaluate the safety, efficacy and cost efficiency of endoscopic diode laser therapy in patients diagnosed with chronic radiation proctitis (CRP). Methods: The data of 24 patients (median age 78, range 67–90 years) who presented rectal bleeding and were diagnosed with CRP after undergoing high-dose radiotherapy for prostatic cancer and underwent diode laser therapy were evaluated retrospectively. Non-contact fibers were used in the patients who underwent the procedure without sedation in an outpatient setting. Results: The patients underwent a median of two sessions; overall, a mean of 1591 J of laser energy per session was used. No complications were noted during or after the procedures. Bleeding was completely resolved in 21/24 (88%) patients, and two patients showed improvement (96%). It was not necessary to suspend antiplatelet (six patients) or anticoagulant (four patients) therapy during the treatment course. The mean cost per session was EUR 473.4. Conclusions: The study findings demonstrated that endoscopic non-contact diode laser treatment in CRP patients is safe, effective and cost efficient. For this procedure, antiplatelet and anticoagulant therapy suspension, intraprocedural sedation and hospital admission are not required.

CITATION EXPORT

Lino Polese, Emilia Giugliano, Roberto Cadrobbi et al.. Diode Laser Therapy for Radiation-Induced Vascular Ectasia: Long-Term Results and Cost Analysis. Life. (2023). https://doi.org/10.3390/life13041025

AUTHORS

4 · 2 CENTRES

Lino Polese, Emilia Giugliano, Roberto Cadrobbi, Deris Gianni Boemo

1First Surgical Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, 35128 Padova, Italy; [email protected] (E.G.); [email protected] (R.C.)
2Medical Direction Unit, Padova University Hospital, 35128 Padova, Italy; [email protected]

EDITOR / REVIEWER

Shinichiro Kashiwagi, Wen-Lun Wang, Hsiu-Po Wang, Jen-Hao Yeh