SEARCHNARRATIVE_REVIEWepidemiology, public health

narrative_review·epidemiology, public health, geriatrics, internal medicine, family medicine·PMC10393839

Disparities in the Prevalence of Osteoporosis and Osteopenia in Men and Women Living in Sub-Saharan Africa, the UK, and the USA

Current Osteoporosis Reports · 7 authors, 7 centres

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TL;DR

This narrative review compiled data from seven studies to compare the prevalence of osteoporosis and osteopenia in adults from sub-Saharan Africa, the UK, and the USA. It found that osteoporosis is generally more prevalent in African populations than previously appreciated, with significant variation by sex, country, and urban/rural setting.

Full summary

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The authors conclude that there is an urgent need for policy reprioritization towards aging populations and equitable access to diagnostic and treatment pathways for bone health in sub-Saharan Africa.

STUDY TYPE

narrative_review

SPECIALTY

epidemiology

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AI pipeline

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ORIGINAL PAPER

PMC10393839

Disparities in the Prevalence of Osteoporosis and Osteopenia in Men and Women Living in Sub-Saharan Africa, the UK, and the USA

Current Osteoporosis Reports

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ABSTRACT

Purpose To review the rising prevalence of osteopenia and osteoporosis in sub-Saharan Africa and the challenges this poses to governments and healthcare services. Using existing studies, we compare the prevalence of osteopenia and osteoporosis in men and women from sub-Saharan Africa to US and UK cohorts. Context-specific disparities in healthcare are discussed particularly the challenges in diagnosis and treatment of osteoporosis. Recent Findings There are few epidemiological data describing the burden of osteoporosis in sub-Saharan Africa. In the studies and cohorts presented here, osteoporosis prevalence varies by sex, country and area of residence, but is generally higher in African populations, than has previously been appreciated. Risk factors contributing to poorer bone health include HIV, malnutrition and “inflammaging.” Summary Reprioritization towards care of ageing populations is urgently required. Equitable access to implementable preventative strategies, diagnostic services, treatments and pathways of care for bone health (for example embedded within HIV services) need now to be recognized and addressed by policy makers. Supplementary Information The online version contains supplementary material available at 10.1007/s11914-023-00801-x.

CITATION EXPORT

Kate A. Ward, Camille M. Pearse, Tafadzwa Madanhire et al.. Disparities in the Prevalence of Osteoporosis and Osteopenia in Men and Women Living in Sub-Saharan Africa, the UK, and the USA. Current Osteoporosis Reports. (2023). https://doi.org/10.1007/s11914-023-00801-x

AUTHORS

7 · 7 CENTRES

Kate A. Ward, Camille M. Pearse, Tafadzwa Madanhire, Alisha N. Wade, June Fabian, Lisa K. Micklesfield, Celia L. Gregson

1grid.123047.30000000103590315MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD UK
2grid.415063.50000 0004 0606 294XMRC Unit The Gambia, London School of Hygiene and Tropical Medicine, Banjul, The Gambia
3grid.8991.90000 0004 0425 469XDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK
4grid.418347.d0000 0004 8265 7435The Health Research Unit Zimbabwe, Biomedical Research & Training Institute, Harare, Zimbabwe
5grid.11951.3d0000 0004 1937 1135MRC/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
6grid.11951.3d0000 0004 1937 1135SAMRC/Wits Developmental Pathways for Health Research Unit, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
7grid.5337.20000 0004 1936 7603Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol, UK