Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease · 10 authors, 12 centres
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In a phase 2 randomized clinical trial of 201 adults with elevated office blood pressure, an adapted mindfulness-based program (MB-BP) was associated with a 4.5 mm Hg greater reduction in systolic blood pressure at 6 months compared with enhanced usual care.
This phase 2 parallel-group randomized clinical trial enrolled 201 participants with elevated unattended office BP (≥120/80 mm Hg) and randomized them to MB-BP (n=101) or enhanced usual care (n=100). The intervention is a mindfulness-based program adapted specifically for individuals with elevated BP. Outcome assessors and the data analyst were blinded to group allocation. At 6 months, MB-BP was associated with a 4.5 mm Hg greater reduction in systolic BP versus control in prespecified analyses, with the MB-BP group showing a 5.9 mm Hg reduction from baseline. Loss-to-follow-up was 17.4%. Results suggest that adapted mindfulness training may offer a clinically relevant approach to BP reduction.
