Effect of direct oral anticoagulants on bleeding during and after cataract surgery

International Ophthalmology · 4 authors, 6 centres

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AGENT 01 · STRUCTURED SUMMARY

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TL;DR

There was no significant difference in hemorrhagic complications between the groups, supporting the safety of continuing DOACs through cataract surgery.

Full summary

331 CHARS

No thromboembolic events occurred in either group. The study is limited by its retrospective design, relatively small sample size, and lack of comparison between continuing and withholding DOACs. The findings support that uninterrupted DOAC therapy during phacoemulsification is feasible and safe, though larger studies are needed.

STUDY TYPE

cohort

SPECIALTY

ophthalmology

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100% · A

ORIGINAL PAPER

PMC10879357

Effect of direct oral anticoagulants on bleeding during and after cataract surgery

International Ophthalmology

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ABSTRACT

Purpose To assess the risk for intraoperative and postoperative ocular bleeding associated with direct oral anticoagulant treatment in patients undergoing phacoemulsification surgery. Methods Consecutive patients had phacoemulsification and intraocular lens implantation while taking uninterrupted direct oral anticoagulants (dabigatran, rivaroxaban, or apixaban). Gender and age-matched patients without antithrombotic therapy were used as the control group. Patients were examined one week postoperatively. Intraoperative and postoperative hemorrhagic and non-hemorrhagic complications were assessed. Results Forty patients (56 eyes) on direct oral anticoagulants and 120 patients (172 eyes) without anticoagulation, at a mean age of 77 years, had phacoemulsification. There was no significant difference between the groups in the rate of intraoperative and postoperative bleeding. One eye (1.8%) in the treatment group and 3 eyes (1.7%) in the control group had hyphema ( p = 0.72). No patient had thromboembolic event during or after surgery. Conclusions Cataract surgery was safely performed while continuing direct oral anticoagulation.

CITATION EXPORT

Anat Maytal, Hadar Naidorf Rosenblatt, Reut Rotem et al.. Effect of direct oral anticoagulants on bleeding during and after cataract surgery. International Ophthalmology. (2024). https://doi.org/10.1007/s10792-024-02944-x

AUTHORS

4 · 6 CENTRES

Anat Maytal, Hadar Naidorf Rosenblatt, Reut Rotem, Fani Segev

1https://ror.org/04pc7j325grid.415250.70000 0001 0325 0791Department of Ophthalmology, Meir Medical Center, Meir Hospital, 59 Tchernichovsky St, 4428164 Kfar Saba, Israel
2https://ror.org/04mhzgx49grid.12136.370000 0004 1937 0546Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
3https://ror.org/00t0n9020grid.415014.50000 0004 0575 3669Department of Ophthalmology, Kaplan Medical Center, Rehovot, Israel
4https://ror.org/03zpnb459grid.414505.10000 0004 0631 3825Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel
5Department of Ophthalmology, Assuta-Samson Medical Center, Ashdod, Israel
6https://ror.org/05tkyf982grid.7489.20000 0004 1937 0511Joyce and Irwing Goldman Medical School, Ben-Gurion University, Beer-Sheva, Israel