This cross-sectional study enrolled 13 inactive and 13 triathlete males to characterize urinary extracellular vesicles (uEVs) as potential noninvasive biomarkers of long-term endurance exercise.
Pflugers Archiv · 19 authors, 9 centres
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This cross-sectional study enrolled 13 inactive and 13 triathlete males to characterize urinary extracellular vesicles (uEVs) as potential noninvasive biomarkers of long-term endurance exercise.
This cross-sectional study enrolled 13 inactive and 13 triathlete males to characterize urinary extracellular vesicles (uEVs) as potential noninvasive biomarkers of long-term endurance exercise. Triathlete uEVs showed smaller size, lower membrane roughness, and a spheroid-like shape compared with inactive-group EVs, which resembled a wrinkled morphology. Four miRNAs (miR-23a-3p, miR-133a, miR-206, miR-34a-5p) were upregulated and two (miR-92a-3p, miR-27a-3p) were downregulated in triathletes.