Annals of Surgery · 15 authors, 4 centres
This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.
This case series reports on 15 patients with end-stage pseudomyxoma peritonei who underwent intestinal or multivisceral transplantation after conventional surgery was not possible. The study found that transplantation is feasible and can lead to improved survival and quality of life for these patients.
This study presents a case series of 15 patients with advanced pseudomyxoma peritonei (PMP) who had nutritional failure and were not suitable for further cytoreductive surgery. Patients underwent radical debulking and intestinal transplantation, including small bowel, modified multivisceral, and abdominal wall transplants as needed. Two patients died within 90 days from surgical complications. Actuarial 1-year and 5-year patient survivals were 79% and 55%, respectively. The majority of patients reported significant quality of life improvement. The study concludes that transplantation is a feasible option for selected patients with no conventional surgical alternatives, though the findings are limited by a small sample size and lack of a comparator group.
