Nano Convergence · 4 authors, 4 centres
This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.
This narrative review summarizes the multi-scale capabilities of functional photoacoustic imaging (fPAI), highlighting its ability to provide quantitative functional information from subcellular organelles to whole human organs. It concludes that advances in fPAI technology have demonstrated significant clinical potential for applications like breast cancer screening and monitoring brain hemodynamics.
This narrative review provides an overview of functional photoacoustic imaging (fPAI) across nano, micro, and macro scales. It describes fPAI as a technique that combines optical contrast with acoustic detection to achieve deeper tissue penetration than pure optical methods. The review summarizes how fPAI has been used to measure physiological parameters such as oxygen saturation, blood flow, and metabolic rate of oxygen in both animal models and humans. It highlights technological advances, such as deep-learning-assisted photoacoustic computed tomography for monitoring rat brain hemodynamics and high-resolution photoacoustic microscopy for evaluating cerebral hemodynamics and tumor angiogenesis. Limitations are not explicitly discussed, but the review implies that future work will focus on improving imaging depth, resolution, and clinical translation.
