Journal of Clinical Medicine · 10 authors, 3 centres
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This narrative review discusses how bronchial asthma is commonly associated with systemic comorbidities (e.g., cardiovascular, metabolic, neurodegenerative diseases) due to shared immunological pathways. It argues that recognizing these connections is essential for personalized clinical management beyond targeted asthma therapies.
This narrative review summarizes recent research on pathobiological interactions between asthma and various systemic comorbidities, including cardiovascular, metabolic, neurodegenerative diseases, and rare disorders like sickle cell disease. It emphasizes a shared immunological background linking these conditions. The authors state that an extensive knowledge of these interactions is essential for clinicians managing asthma patients to tailor diagnostic work-ups and long-term assessment. The review concludes that awareness of these links between different diseases and their common immunological background is essential for personalized medicine, integrating targeted treatments, ordinary therapy, and non-pharmacological approaches.
