High incidence of pulmonary tuberculosis in an indigenous Saharia tribe in Madhya Pradesh, central India—A prospective cohort study

PLOS Global Public Health · 5 authors, 5 centres

AI SUMMARY

FIDELITY 100%

POPULATIONSaharia tribal population aged 15 years and above in Shivpuri district, Madhya Pradesh, India.

INTERVENTION

COMPARISON

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

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TL;DR

This prospective cohort study calculated the incidence of pulmonary tuberculosis (PTB) in the Saharia tribal population in India over a one-year period. The study found a very high overall incidence of bacteriologically confirmed PTB, which was significantly higher in males and increased with age.

Full summary

640 CHARS

A prospective cohort study was conducted among the Saharia tribal population (aged 15 years and above) in Madhya Pradesh, India. A baseline prevalence survey in 2012–13 identified and excluded 293 individuals with bacteriologically positive PTB. The overall incidence of bacteriologically positive PTB over one year was 1504 per 100,000 population (95% CI: 1273–1776). The incidence was 2.8 times higher in males compared to females and positively correlated with age, peaking at 2421 per 100,000 in those aged 55 and above. The study highlights a TB incidence substantially higher than the national average in this disadvantaged community.

PICO

PPOPULATION

Saharia tribal population aged 15 years and above in Shivpuri district, Madhya Pradesh, India.

OOUTCOME

Incidence of bacteriologically positive (smear and/or culture) pulmonary tuberculosis per 100,000 population over one year.

STUDY TYPE

cohort

SPECIALTY

epidemiology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10022087

High incidence of pulmonary tuberculosis in an indigenous Saharia tribe in Madhya Pradesh, central India—A prospective cohort study

PLOS Global Public Health

READ THE FULL PAPER

ABSTRACT

Background Lack of TB incidence data is an important evidence gap among Saharia–a high TB burden indigenous community in Madhya Pradesh, central India. The present study was undertaken to calculate the incidence of pulmonary tuberculosis in this tribe. Objective To calculate the incidence of pulmonary tuberculosis (PTB) among the Saharia tribal population in Madhya Pradesh, central India. Methods A prospective cohort study was conducted among the Saharia tribal population (aged 15 years and above) of Shivpuri district in Madhya Pradesh state in central India. A total of 9,756 individuals were screened for TB in the baseline TB prevalence survey during 2012–13. All available household members were screened for symptoms suggestive of pulmonary TB (presumptive TB). Two sputum specimens were collected from persons having symptoms suggestive of TB and examined by smear and culture tests. A cohort of all non-TB individuals in the baseline survey was followed-up for one year and re-screened for the sysmptoms of PTB in the year 2014–15. Based on the data collected, the incidence of TB over one year period was estimated per 100,000 population. Results A total of 9756 and 9044 individuals (≥ 15 years) were screened for symptoms suggestive of PTB during baseline and endline surveys respectively. The sputum specimens of presumptive TB cases were collected and examined by smear and culture tests. The overall incidence of bacteriologically positive (smear and/or culture) PTB over one year period was 1504 (95% Confidence Interval (CI): 1273–1776) per 100,000 in the study population, the incidence of smear-positive PTB was 1106 (95% CI: 910–1343), and the incidence of culture-positive PTB was 1084 (95% CI: 890–1319) per 100,000 population. The incidence for both smear and culture-positive PTB was 686 (95% CI: 535–878) per 100,000 population in the year 2014–15. The incidence of PTB was 2.8 times higher in males compared to females (2259 vs 807 per 100,000) and was positively correlated with age. Conclusion The findings of the study, the first of its kind in the Saharia tribal population, indicate a high incidence of TB in this tribal community thereby highlighting the urgent need for focused and intensified efforts to achieve the goal of TB elimination in the country.

CITATION EXPORT

Jyothi Bhat, Rajiv Yadav, Ravendra K. Sharma et al.. High incidence of pulmonary tuberculosis in an indigenous Saharia tribe in Madhya Pradesh, central India—A prospective cohort study. PLOS Global Public Health. (2022). https://doi.org/10.1371/journal.pgph.0000039

AUTHORS

5 · 5 CENTRES

Jyothi Bhat, Rajiv Yadav, Ravendra K. Sharma, Malaisamy Muniyandi, V. G. Rao

1 ICMR–National Institute of Research in Tribal Health, Jabalpur, India
2 ICMR- National Institute of Traditional Medicine, Belgavi, India
3 Ch Charan Singh University, Meerut (U.P.), India
4 ICMR–National Institute for Research in Tuberculosis, Chennai, India
University of California Irvine, UNITED STATES

EDITOR / REVIEWER

Sanghyuk Shin