Annals of Medicine and Surgery · 8 authors, 13 centres
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This correspondence reviews the immunomodulatory effects of common general anaesthetics (like propofol, ketamine, and volatile agents) in the context of COVID-19. It discusses how these drug effects may influence perioperative infection risks and surgical outcomes for patients with current or prior SARS-CoV-2 infection.
It outlines that SARS-CoV-2 infection, particularly within 8 weeks of surgery, significantly increases postoperative complications and mortality. The authors emphasize that these immunosuppressive effects could exacerbate infections in COVID-19 patients. The implications highlight the need for caution in anaesthetic choice to minimize infection risk.
