Clinical Kidney Journal · 13 authors, 33 centres
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A population-based retrospective cohort study of propensity-matched CKD patients in Taiwan found that influenza vaccination was associated with significantly lower RCC incidence, with an adjusted HR of 0.46. The protective effect was more pronounced in patients aged 75 years and older.
This population-based retrospective cohort study used the Taiwan National Health Insurance Database (2003–2014) to evaluate the association between influenza vaccination and RCC risk in CKD patients aged ≥55 years. Limitations include the observational design, potential residual confounding from unmeasured variables such as smoking, environmental exposures, and family history of cancers, and the lack of information on the underlying pathophysiological mechanisms. Future randomized clinical trials and mechanistic studies are needed to confirm these associations.
