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TL;DR
It concludes that infusion therapies offer benefits for patients with inadequate control on oral medications, with considerations for patient selection and management.
Journal of Parkinson's Disease · 5 authors, 6 centres
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It concludes that infusion therapies offer benefits for patients with inadequate control on oral medications, with considerations for patient selection and management.
It discusses the rationale for these therapies, noting that oral levodopa can become less effective due to motor fluctuations and dyskinesias as the disease progresses. The review highlights that infusion and surgical therapies are alternatives for aPD when oral treatments are insufficient. Limitations noted include a lack of consensus on identifying aPD and the underuse of advanced treatments. The implications are that infusion therapies are beneficial but require proper patient selection and multidisciplinary management.