This is a consensus-based national clinical practice guideline developed by Iranian experts to standardize multidisciplinary care for amyotrophic lateral sclerosis (ALS) patients.
Frontiers in Neurology · 21 authors, 24 centres
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This is a consensus-based national clinical practice guideline developed by Iranian experts to standardize multidisciplinary care for amyotrophic lateral sclerosis (ALS) patients.
A multidisciplinary team of Iranian experts developed a national clinical practice guideline for amyotrophic lateral sclerosis (ALS). Methods involved formulating PICO questions, searching medical literature, and using a consensus-based approach to evaluate evidence and formulate recommendations due to a lack of adequate local studies. Recommendations were graded based on expert consensus for scientific rigor, quality of evidence, and feasibility factors like availability, cultural acceptance, legal aspects, and costs. The conclusion states that while there is no cure, multidisciplinary care focusing on key domains improves quality of life and survival. The guideline is intended as a knowledge base for developing local clinical pathways in Iranian multidisciplinary ALS clinics.