This is a policy statement from major health organizations recommending against using spot urine samples with estimating equations for individual sodium intake assessment in research due to large errors and spurious health outcome associations.
Journal of Hypertension · 11 authors, 9 centres
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This is a policy statement from major health organizations recommending against using spot urine samples with estimating equations for individual sodium intake assessment in research due to large errors and spurious health outcome associations.
It reviews literature concluding that spot urine samples with estimating equations have large random and systematic error, are not reproducible, and lack scientific rationale for predicting long-term sodium intake. The statement asserts that this method causes spurious associations with disease outcomes. Based on this evidence, the organizations issue a strong recommendation that research using this method to assess individual sodium intake in association with health outcomes should not be conducted, funded, or published. The conclusion notes consistent evidence indicating the method is not valid.