Nutrients · 3 authors, 3 centres
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This narrative review examines evidence from observational studies, RCTs, and meta-analyses on how nutrients like omega-3, vitamin D, B vitamins, zinc, magnesium, chromium, and selenium may help manage both blood glucose and mental health in people with type 2 diabetes. The central finding is that adequate intake or targeted supplementation of these nutrients may concurrently support metabolic and mental well-being.
The study is a narrative literature review synthesizing evidence from observational studies, RCTs, systematic reviews, and meta-analyses published between 2008 and 2023. It investigates the role of specific nutrients (omega-3 fatty acids, vitamin D, B vitamins, zinc, magnesium, chromium, selenium, iron) in improving glucose homeostasis and mental health outcomes, such as depression and anxiety, in individuals with type 2 diabetes. The review indicates that deficiencies in these nutrients are implicated in the pathogenesis of both diabetes and mental disorders. Available evidence suggests certain nutrients may have beneficial effects on both conditions, but the authors emphasize that more clinical trials are needed to confirm effects and determine optimal dosages, especially for comorbid cases. A key limitation is the noted knowledge gap on the simultaneous management of these conditions. The implication is that personalized dietary interventions and targeted supplementation, when dietary intake is insufficient, may be vital components of comprehensive care.
