SEARCHCROSS-SECTIONALepidemiology, public health

cross-sectional·epidemiology, public health, internal medicine, infectious disease, nephrology·PMC10434868

Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia

PLOS Global Public Health · 10 authors, 5 centres

AI SUMMARY

FIDELITY 100%

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

“

TL;DR

This institutional cross-sectional study found an 8.1% mortality rate among 393 COVID-19 patients hospitalized in Addis Ababa, Ethiopia. Factors independently associated with death included older age (>50 years), male sex, and having diabetes, hypertension, or chronic kidney disease.

Full summary

841 CHARS

The study was an institutional-based cross-sectional analysis of 393 patient records from Eka Kotebe General Hospital in Addis Ababa, Ethiopia, covering admissions from January 15 to June 30, 2021. The primary outcome was mortality, with an observed rate of 8.1% (95% CI: 5.4–10.8%). Using multivariable logistic regression, the study identified several factors significantly associated with increased odds of death: age over 50 years (AOR = 7.91), male sex (AOR = 2.09), diabetes mellitus (AOR = 2.64), hypertension (AOR = 2.67), and chronic kidney disease (AOR = 12.04). Additionally, the study population included only hospitalized patients who tested positive, potentially missing cases in the community. The findings suggest that older patients and those with specific comorbidities may benefit from targeted preventative interventions.

STUDY TYPE

cross-sectional

SPECIALTY

epidemiology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10434868

Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia

PLOS Global Public Health

READ THE FULL PAPER

ABSTRACT

Abstract The COVID-19 pandemic continues to grow around the world and has caused enormous mortality and morbidity. The severity and mortality of coronavirus disease are associated with various comorbidities. The infection fatality rate was reported to be inconsistent with different studies. Therefore, the aim of this study was to assess the magnitude and factors associated with mortality among patients admitted to Eka Kotebe General Hospital, Addis Ababa, Ethiopia. An institutional-based cross-sectional study was conducted at Eka Kotebe General Hospital among patients who were admitted for COVID-19 from January 15, 2021, to June 30, 2021. A total of 393 records of patients were selected by simple random sampling. Data was extracted from compiled data forms where available information was already tabulated. Data was entered and analyzed using SPSS version 25. The determinant factors associated with mortality among COVID-19 patients were identified using bivariate and multivariable logistic regression analysis. A statistical association was declared with multivariable logistic regression using a 95% confidence interval and a P-value of less than 0.05. The proportion of COVID-19 mortality among patients admitted to Eka Kotebe General Hospital was 8.1% (95% CI (5.4–10.8%)). Age >50 years [AOR = 7.91; 95% CI (2.34–25.70)], being male [AOR = 2.09; 95% CI (1.20–3.65)], having diabetes mellitus [AOR = 2.64; 95% CI (1.30–5.35)], having hypertension [AOR = 2.67; 95% CI (1.22–5.88)] and having chronic kidney disease [AOR = 12.04; 95% CI (4.03–14.22)] were determinant factors of COVID-19 mortality. The current study findings revealed that COVID-19 mortality was high among hospitalized COVID-19 patients. Furthermore, age, gender, diabetes mellitus, hypertension, and chronic kidney disease were discovered to be independent predictors of COVID-19 mortality. Therefore, older COVID-19 patients and those with established comorbidities such as hypertension, diabetes, and end-stage renal disease should receive comprehensive preventative efforts, including vaccination.

CITATION EXPORT

Genanew Kassie Getahun, Amare Dinku, Dube Jara et al.. Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia. PLOS Global Public Health. (2023). https://doi.org/10.1371/journal.pgph.0000420

AUTHORS

10 · 5 CENTRES

Genanew Kassie Getahun, Amare Dinku, Dube Jara, Tewodros Shitemaw, Zelalem Negash, Julia Robinson, Caroline Bull, Hugh Cowley, Flavio Finger, Flavio Finger

1Menelik II Medical and Health Science College, Kotebe Metropolitan University, Addis Ababa, Ethiopia
2Yanet Health College, Addis Ababa, Ethiopia
3Debre Markos University, Debre Markos, Ethiopia
4Yekatit 12 Medical College, Addis Ababa, Ethiopia
5Epicentre MSF, SWITZERLAND