Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges
Military Medical Research · 10 authors, 6 centres
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The authors describe multiple biological mechanisms by which MSC-EVs may promote healing, including regeneration of vessels and nerves, inhibition of scar formation, and modulation of inflammation and cell proliferation.
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The authors describe multiple biological mechanisms by which MSC-EVs may promote healing, including regeneration of vessels and nerves, inhibition of scar formation, and modulation of inflammation and cell proliferation. The authors conclude that while MSC-EVs show promise as a cell-free therapy, significant hurdles in standardization, purity, yield, and biosafety must be overcome before widespread clinical use.
