This editorial introduces a special issue comprising 7 scientific papers and 3 reviews exploring mitochondrial function and signaling across topics including metabolism, aging, nutrition, and disease.
Life · 1 author, 1 centre
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This editorial introduces a special issue comprising 7 scientific papers and 3 reviews exploring mitochondrial function and signaling across topics including metabolism, aging, nutrition, and disease.
This editorial provides an overview of a special issue containing 7 scientific papers and 3 reviews on mitochondrial function and cellular signaling. The summarized studies span multiple organisms including Saccharomyces cerevisiae, rats, and indirectly human-relevant models. Key themes include the role of lifestyle factors such as nutrition and exercise in regulating mitochondrial function, the impact of mitochondrial dysfunction on aging and disease, and the development of new techniques for studying mitochondria. Specific findings highlighted include that moderate aerobic exercise with a high-protein diet may reduce inflammation and oxidative stress in osteoarthritis, that hydroxytirosol enhances glucose oxidation mRNA but hampers protein translation, and that avocado oil may prevent hypertensive renal damage through reduced mitochondrial ROS.