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TL;DR
This large cohort study analyzed real-world data from over one million patients to find that psoriasis prevalence was 2.84%, and patients frequently had multimorbidity, with disorders of lipid metabolism being the most common comorbidity.
Journal of Clinical Medicine · 9 authors, 4 centres
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This large cohort study analyzed real-world data from over one million patients to find that psoriasis prevalence was 2.84%, and patients frequently had multimorbidity, with disorders of lipid metabolism being the most common comorbidity.
This observational cohort study used real-world data from 1,098,383 patients in the Spanish public health system to examine psoriasis prevalence and comorbidities. The study identified 31,178 patients with psoriasis, finding a prevalence of 2.84%. A key result was the high multimorbidity in patients, with almost three in four presenting multiple diseases. The most common comorbidity was disorders of lipid metabolism, with a prevalence of 35.87%. Significant associations were found for other liver diseases, osteoarthritis, and infections like otitis externa. Conversely, no statistically significant association was found with hypertension or cardiovascular diseases like acute myocardial infarction. Limitations include potential underdiagnosis of conditions like psoriatic arthritis and the reliance on physician-detected diagnoses for psychiatric comorbidities. The findings highlight the complex comorbidity profile of psoriasis but do not establish causal relationships.