Muscle Cramps in Outpatients with Liver Diseases in Tokyo, Japan

Medicina · 12 authors, 1 centre

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TL;DR

This retrospective study found that muscle cramps affected 14.3% of 238 outpatients with liver diseases, with older age (≥66 years) being the only significant associated factor. Notably, about two-thirds of affected patients did not receive any therapy for their cramps.

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A retrospective cohort study of 238 outpatients with liver diseases at a Tokyo university hospital assessed the prevalence and treatment of muscle cramps. Muscle cramps were identified in 34 patients (14.3%), with a mean visual analog scale pain score of 5.53. Multivariate analysis revealed that older age (≥66 years) was the only factor significantly associated with muscle cramps. The study highlights that 32.4% of patients with cramps received therapy, indicating a potential gap in clinical management.

STUDY TYPE

cohort

SPECIALTY

gastroenterology

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100% · A

ORIGINAL PAPER

PMC10532783

Muscle Cramps in Outpatients with Liver Diseases in Tokyo, Japan

Medicina

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ABSTRACT

Background and Objectives: Muscle cramps are often observed in patients with liver diseases, especially advanced liver fibrosis. The exact prevalence of muscle cramps in outpatients with liver diseases in Japan is unknown. Patients and Methods: This study examined the prevalence of, and therapies for, muscle cramps in outpatients with liver diseases in Tokyo, Japan. A total of 238 outpatients with liver diseases were retrospectively examined. We investigated whether they had muscle cramps using a visual analog scale (VAS) (from 0, none, to 10, strongest), and also investigated their therapies. Results: Muscle cramps were observed in 34 outpatients with liver diseases (14.3%); their mean VAS score was 5.53. A multivariate analysis demonstrated that older age (equal to or older than 66 years) was the only significant factor as-sociated with muscle cramps. The prevalence of muscle cramps among patients with liver diseases seemed not to be higher. The problem was that only 11 (32.4%) of 34 outpatients received therapy for their muscle cramps. Conclusions: Only age is related to muscle cramps, which is rather weak, and it is possible that this common symptom may not be limited to liver disease patients.

CITATION EXPORT

Tatsuo Kanda, Reina Sasaki-Tanaka, Naoki Matsumoto et al.. Muscle Cramps in Outpatients with Liver Diseases in Tokyo, Japan. Medicina. (2023). https://doi.org/10.3390/medicina59091506

AUTHORS

12 · 1 CENTRES

Tatsuo Kanda, Reina Sasaki-Tanaka, Naoki Matsumoto, Shuhei Arima, Shini Kanezawa, Masayuki Honda, Mai Totsuka, Tomotaka Ishii, Ryota Masuzaki, Masahiro Ogawa, Hiroaki Yamagami, Hirofumi Kogure

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan; [email protected] (R.S.-T.); [email protected] (N.M.); [email protected] (S.A.); [email protected] (S.K.); [email protected] (M.H.); [email protected] (M.T.); [email protected] (T.I.); [email protected] (R.M.); [email protected] (M.O.); [email protected] (H.Y.); [email protected] (H.K.)

EDITOR / REVIEWER

Endrit Shahini, Antonio Giovanni Solimando, Antonella Argentiero