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TL;DR
The authors note that NCWS is a better umbrella term as symptoms can be triggered by wheat components other than gluten, such as fructans and ATIs.
Current Opinion in Clinical Nutrition and Metabolic Care · 3 authors, 3 centres
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The authors note that NCWS is a better umbrella term as symptoms can be triggered by wheat components other than gluten, such as fructans and ATIs.
The authors note that NCWS is a better umbrella term as symptoms can be triggered by wheat components other than gluten, such as fructans and ATIs. The review highlights the well-established overlap between NCWS and IBS. It cites a Spanish study finding that 62% of IBS patients improved after starting a gluten-free diet (GFD), but notes the lack of a control group limits causal conclusions. A recent randomized trial comparing traditional dietary advice (TDA), a low-FODMAP diet (LFD), and a GFD for non-constipated IBS found similar short-term efficacy, with TDA being easier to follow. The review concludes that while the GFD can improve symptoms and quality of life for some individuals, key aspects of NCWS, such as epidemiology, a biomarker, and natural history, remain undefined.