Journal of Hematology & Oncology · 3 authors, 6 centres
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This narrative review proposes a conceptual framework called 'counter-immunoediting therapy' to address immunotherapy resistance. It suggests that by identifying the phase of cancer immunoediting (elimination, equilibrium, escape) in a patient's tumor, clinicians can select targeted treatment strategies to reverse the process and potentially cure cancer.
This narrative review synthesizes the concept of cancer immunoediting, which describes a dynamic interaction between tumor cells and the immune system through elimination, equilibrium, and escape phases, leading to therapy resistance. The central implication is that retrograding the immunoediting process could enable long-term remission.
