Reumatologia · 3 authors, 1 centre
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This narrative review summarizes evidence that obesity is a major risk factor for the onset and worsening of many musculoskeletal and rheumatological diseases. It concludes that weight reduction has beneficial effects on the musculoskeletal system.
This narrative review synthesizes evidence from a PubMed search for epidemiological and observational studies on obesity and musculoskeletal disorders. The underlying mechanisms are described as complex, involving biomechanical, inflammatory, metabolic, and genetic factors. The authors conclude that obesity, as a chronic disease requiring energetic treatment, demands lifestyle modification often supplemented with pharmacological or surgical interventions.
