Life · 5 authors, 6 centres
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This nested case-control study of 399 pregnant women investigated the effects of workplace exposure to chemical, biological, and physical risks on newborn health. The central result was a statistically significant lower arterial PO2 value in the umbilical cord blood of neonates from mothers exposed to physical risks compared to those exposed to chemical/biological risks.
This hospital-based nested case-control study analyzed a retrospective cohort of 399 pregnant women in Valencia, Spain. Participants were categorized into three groups based on reported occupational exposure during pregnancy: 138 exposed to chemical/biological risks, 122 to physical risks, and 139 with no exposure. The study collected sociodemographic, obstetric, and newborn health data, including umbilical cord blood gas analysis at delivery. However, neonates from mothers with physical risk exposure had a significantly lower mean arterial PO2 (20.46 ± 8.70 mmHg) compared to the chemical/biological risk group (21.96 ± 10.18 mmHg; p=0.027). The study also noted a lower frequency of in vitro fertilization use in the chemical/biological risk group (p=0.047). The findings contribute to evidence for occupational health planning but suggest the need for larger studies with more detailed exposure assessments.
